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| Product Name | Acrp30, Recombinant, Human |
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| Description | Purity ~97% (SDS-PAGE and HPLC). Adiponectin is an adipose-derived secreted protein containing 226aa. It is relatively abundant in humans and rodents, accounting for about 0.01% of total plasma protein. The circulating levels of adiponectin are decreased under conditions of obesity, insulin resistance, and type II diabetes. Disruption of adiponectin in mice causes insulin resistance and neointimal formation. Conversely, administration of recombinant adiponectin suppresses hepatic glucose production, and reverses insulin resistance associated with both lipoatrophy and obesity. The protective role of adiponectin is attributed to its anti-inflammatory properties (e.g. ability to suppress expression of TNF-alpha and class A scavenger receptor in macrophages). Recombinant adiponectin is a multimeric glycoprotein containing aa Glu-19 to Asn-244 of the adiponectin precursor protein fused to an N-terminal histidine tag. Monomeric glycosylated adiponectin migrates at an apparent molecular weigh |
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| Size | 5ug, 25ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Acrp30, Recombinant, Human (30kD Adipocyte Complement-related Protein, ACDC, Adipocyte C1q and Collagen Domain Containing Protein, Adiponectin, ADPN, ADIPOQ, Adipose Most Abundant Gene Transcript 1 Protein, ADIPQTL1, APM1, apM-1, Gelatin-binding Protein, GBP28) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 149668 |
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| Price | |
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| Order / More Info | Acrp30, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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