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| Product Name | Acrp30, Recombinant, Human, His-Tag |
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| Description | Purity ~95% (nickel-columns). Acrp30 was identified as a novel adipocyte-specific synthesized and secreted protein with structural resemblance to complement factor C1q. Like adipsin, Acrp30 secretion is induced ~10-fold during adipocyte differentiation. Plasma levels are reduced in obese humans, and low levels are associated with insulin-resistance. Treatment of db/db mice with TZD increased Acrp30 levels. Acrp30 (mouse 247aa, rat human 244aa; chromosome 3q27) consists of a predicted NT-signal sequence aa91-14), followed by a 27-aa unique region, and then by 22 perfect Gly-X-Pro or Gly-X-X collagen like repeats, and a globular segment at the C-terminus. Structurally, but at the sequence level, Acrp30 resembles other collagen-like and globular domain proteins (lung surfactant protein and hepatocytes mannan- binding proteins). Acrp30 is proteolytically cleaved at 104aa to generate the globular Acrp30 (gAcrp30). Administration of gAcrp30 into mice fed a diet high in fat and sugar caused s |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Acrp30, Recombinant, Human, His-Tag (Adipocyte Complement-related Protein of 30kD, AdipoQ, APM1, Adiponectin, Gelatin Binding Protein 28kD, GBP28, Adipocyte Most Abundant Gene Transcript) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 208715 |
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| Order / More Info | Acrp30, Recombinant, Human, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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