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| Product Name | LMP1, Recombinant, Epstein-Barr Virus, aa185-366, His-Tag (Latent Membrane Protein 1) |
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| Description | Purity ~90% (SDS-PAGE). Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several signaling pathways, including those of the NF-kappa-B family. LMP1 signaling leads to up-regulation of antiapoptotic proteins and provide growth signals in latently infected cells. Interacts with host UBE2I and subsequently affects the sumoylation state of several cellular proteins. For example, induces the sumoylation of host IRF7 thereby limiting its transcriptional activity and modulating the activation of innate immune responses. Source: Recombinant protein corresponding to aa185-366 from epstein-barr virus LMP1, fused to His-Tag at N-terminal, expressed in Yeast. Molecular Weight: ~20.8kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Protein p63 |
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| Gene, Accession, CAS # | SwissProt: P0C741 |
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| Catalog # | 374062 |
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| Order / More Info | LMP1, Recombinant, Epstein-Barr Virus, aa185-366, His-Tag (Latent Membrane Protein 1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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