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Product Name | Recombinant Human ICOS / AILIM / CD278 Protein (His & Fc tag) |
Description | MW: 19,127 Da. Purity >94 % as determined by SDS-PAGE. Background: Inducible costimulator (ICOS), also called AILIM (activiation-inducible lymphocyte immunomediatory molecule) is a cell-surface receptor, and belongs to the CD28 family of immune costimulatory receptors consisting of CD28, CTLA-4 and PD-1. The interaction of B7-H2/ICOS plays a critical role in Th cell differentiation, T-B cell interactions which is essential for germinal center formation, and humoral immune responses, and as well |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | The recombinant human ICOS/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 368 amino acids and predicts a molecular mass of 41.6 kDa. The apparent molecular mass of rhICOS/Fc monomer is approximately 50 kDa due to glycosylation. |
Other Names | [AILIM, CD278, MGC39850] |
Gene, Accession, CAS # | ICOS / AILIM / CD278, Gene ID: 29851, Accession: NP_036224.1 |
Catalog # | MBS2546316 |
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Order / More Info | Recombinant Human ICOS / AILIM / CD278 Protein (His & Fc tag) from MYBIOSOURCE INC. |
Product Specific References | n/a |
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