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Product Name | Recombinant Human ICOS Ligand / B7-H2 / ICOSLG Protein (His tag) |
Description | MW: 20,120 Da. Purity >98 % as determined by SDS-PAGE. Background: Inducible co-stimulator ligand (ICOSL), also known as B7-H2, is a member of the B7 family of co-stimulatory molecules related to B7-1 and B7-2. It is a transmembrane glycoprotein with extracellular IgV and IgC domains, and binds to ICOS on activated T cells, thus delivers a positive costimulatory signal for optimal T cell function. The structural features of ICOSL are crucial for its costimulatory function. Present study shows th |
Size | 0.1 mg, 0.2 mg |
Concentration | n/a |
Applications | The secreted recombinant human ICOSLG consists of 251 amino acids and has a calculated molecular mass of 28 kDa. The apparent molecular mass of the protein is approximately 50-60 kDa in SDS-PAGE under reducing conditions as predicted. |
Other Names | [B7-H2, B7H2, B7RP-1, B7RP1, CD275, GL50, ICOS-L, ICOSL, KIAA0653, LICOS] |
Gene, Accession, CAS # | ICOSLG, Gene ID: 23308, Accession: NP_056074.1 |
Catalog # | MBS2545745 |
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Order / More Info | Recombinant Human ICOS Ligand / B7-H2 / ICOSLG Protein (His tag) from MYBIOSOURCE INC. |
Product Specific References | n/a |
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