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| Product Name | SPG21, 1-308aa, Human, His tag, E Coli |
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| Description | MW: 37.1 kDa (328aa), confirmed by MALDI-TOF. Purity >95% by SDS-PAGE. Spastic paraplegia 21 (SPG21), also known as Maspardin, binds to the hydrophobic C-terminal amino acids of CD4 and may play a role as a negative regulatory factor in CD4-depenent T-cell activation. This protein is widely expressed in various tissues including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Mutations in SPG21 cause Mast syndrome, an autosomal-recessive complicated form of hereditary |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Spastic paraplegia 21 isoform a; ACP33; BM-019; GL010; Maspardin; MAST; Spastic paraplegia 21 isoform a Acid cluster protein 33; BM019; Spastic paraplegia 21 autosomal recessive Mast syndrome protein; SPG21.] |
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| Gene, Accession, CAS # | SPG21, Gene ID: 51324, Accession: NP_057714 |
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| Catalog # | MBS203178 |
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| Order / More Info | SPG21, 1-308aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Simpson MA., et al. (2003). Am J Hum Genet. 73 (5):1147-56.; Zeitlmann L., et al. (2001). J Biol Chem. 276 (12):9123-32.; |
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