| 产品详情 |
| Edit |   |
| Product Name | SPG21, 1-308 aa, Recombinant, Human |
| Description | Purified. ≥95% by SDS-Page. Spastic paraplegia 21(SPG21), also known as Maspardin, binds to the hydrophobic C-terminal amino acids of CD4 and may play a role as a negative regulatory factor in CD4-depenent T-cell activation. This protein is widely expressed in various tissues including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Mutations in SPG21 cause Mast syndrome, an autosomal-recessive complicated form of hereditary spastic paraplegia characterized by dementia, thin corpus callosum and white matter abnormalities. Recombinant human SPG21 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography. Molecular Weight: 37.1kD (328aa) AA Sequence: MGSSHHHHHH SSGLVPRGSH MGEIKVSPDY NWFRGTVPLK KIIVDDDDSK IWSLYDAGPR SIRCPLIFLP PVSGTADVFF RQILALTGWG YRVIALQYPV YWDHLEFCDG FRKLLDHLQL DKVHLFGASL GGFLAQKFAE YTHKSPRVHS LILCNSFSDT SIFNQTWTAN SFWLMPAFML KKIVLGNFSS GPVDPMMADA IDFMVDRLES LGQSELASRL TLNCQNSYVE PHKIR |
| Size | 100ug |
| Concentration | n/a |
| Applications | n/a |
| Other Names | SPG21, 1-308 aa, Recombinant, Human (Spastic paraplegia 21 isoform a, ACP33, BM-019, GL010, Maspardin, MAST, Acid cluster protein 33, ACP33, BM-019, GL010, Maspardin, MASPARDIN, MAST, Spastic paraplegia 21 autosomal recessive Mast syndrome protein) |
| Gene, Accession, CAS # | Accession: NP_057714 |
| Catalog # | S4283 |
| Price | |
| Order / More Info | SPG21, 1-308 aa, Recombinant, Human from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
| 产品资料 |
|
|