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| Product Name | Human LIFR Recombinant (CD118) |
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| Description | MW: 123,743 Da. Purity >90%, as determined by SDS-PAGE and HPLC. LIF acts on its target cells via the activation of the LIF-receptor (LIFR) complex. The LIFR complex requires heterodimerisation of the two low affinity components LIFR and glycoprotein 130 (gp130), where combination transforms a low-affinity binding complex into a high- affinity binding site. Activation of the LIFR complex can trigger several signal transduction paIn LIF-induced heterodimerization with the LIFR, only the CBM of gp |
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| Size | 0.02 mg, 0.1 mg, 0.5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Human CD118 Recombinant (LIFR) ; LIFR; CD118; FLJ98106; FLJ99923; LIF-R; SJS2; STWS; SWS] |
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| Gene, Accession, CAS # | CD118, Gene ID: 3977, Accession: NP_001121143.1 |
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| Catalog # | MBS553097 |
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| Order / More Info | Human LIFR Recombinant (CD118) from MYBIOSOURCE INC. |
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| Product Specific References | • determining the lif-sensitive period for implantation using a lif-receptor antagonist .Reproduction, Nov 2009; 138: 827 - 836. • loss of myocardial LIF receptor in experimental heart failure reduces cardiotrophin-1 cytoprotection. a role for neurohumoral agonists? .Cardiovasc Res, Aug 2007; 75: 536 - 545. • an unusual cytokine:ig-domain interaction revealed in the crystal structure of leukemia inhibitory factor (lif) in complex with the LIF receptor .PNAS, Jul 2007; 104: 12737 - |
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