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| Product Name | 6,6'-Trehalose Dimycolate (Cord-Factor, TDM) |
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| Description | Purity ~90% Single spot, TLC Endotoxin: ≤10e-4 EU/ug (LAL). 6,6`-Trehalose Dimycolate (Cord Factor, source: Mycobacterium bovis, Bacillus Calmette Guerin) 6,6'-dimycoloyl-α-D-trehalose (Mycobacterium bovis, BCG) is used as an immunoadjuvant for the induction and non-specific stimulation of antibody production against unrelated antigens. This results in an increased host resistance against infections and cancer, in the potentiation of vaccine immunogeneticity and in an increase of DNA vaccination efficacy. 6`6-Trehalose dimycolate (TDM) exhibits strong immunomodulatory effects, greatly enhancing the efficacy of DNA vaccination, shown to facilitate single-shot prime-boost DNA vaccines (3). TDM from M. bovis has a lower granulomatogenic activity as compared to TDM from M. tuberculosis (5). Preinjection of TDM followed by antigen injection triggers elevated antibody production (2). TDM stimulates macrophages, enhances non-specific immune responses and stimulates the antigen-presentin |
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| Size | 1mg, 2.5mg, 5mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | T8270-10 |
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| Order / More Info | 6,6'-Trehalose Dimycolate (Cord-Factor, TDM) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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