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| Product Name | Recombinant Centruroides suffusus suffusus (Mexican scorpion) Beta-mammal toxin Css4 |
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| Description | 1-66aa; Full Length. MW: 23.61kD. Purity >90% as determined by SDS-PAGE. Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing. This toxin is active only on mammals. |
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| Size | 0.01 mg (Yeast), 0.05 mg (Yeast), 0.1 mg (Yeast), 0.2 mg (Yeast), 0.05 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Beta-mammal toxin Css4; Beta-mammal toxin Css4; Css IV; CssIV] |
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| Gene, Accession, CAS # | CssIV, Accession: P60266.1 |
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| Catalog # | MBS1045370 |
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| Order / More Info | Recombinant Centruroides suffusus suffusus (Mexican scorpion) Beta-mammal toxin Css4 from MYBIOSOURCE INC. |
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| Product Specific References | Scorpion toxins specific for Na -channels.Possani L.D., Becerril B., Delepierre M., Tytgat J.Eur. J. Biochem. 264:287-300(1999) Purification and chemical and biological characterizations of seven toxins from the Mexican scorpion, Centruroides suffusus suffusus.Martin M.-F., Garcia Y., Perez L.G., el Ayeb M., Kopeyan C., Bechis G., Jover E., Rochat H.J. Biol. Chem. 262:4452-4459(1987) Voltage sensor-trappingenhanced activation of sodium channels by beta-scorpion toxin bound to the S3-S4 loop in d |
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