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| Product Name | Growth and Differentiation Factor 9, Recombinant, Mouse (GDF9) |
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| Description | Purified ≥ 95% as determined by SDS-PAGE under reducing conditions and visualized by silver stain. Mouse GDF-9 Growth differentiation factor-9 (GDF-9) is a member of the transforming growth factor-beta (TGF-beta) superfamily, and is an oocyte secreted paracrine factor essential for mammalian ovarian folliculogenesis (1-2). Mouse GDF-9 is synthesized as a 441aa prepropeptide that contains a 29aa signal sequence, a 277aa propeptide, and a 135aa mature chain (SwissProt # Q07105). Residues 340-441 constitute a TGF-beta like domain. In addition, there is one potential site of N-linked glycosylation in the mature chain. Unlike other members of the TGF-beta superfamily, GDF-9 lacks the conserved cysteine residue that is believed to form the sole disulfide linkage between subunits in other family members (3). Mature mouse GDF-9 shares 90% aa sequence identity with mature human GDF-9. The protein is expressed throughout the development of the maturing follicle (2). GDF-9 functions as a paracrin |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: AAA53035 |
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| Catalog # | G8989-49E |
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| Order / More Info | Growth and Differentiation Factor 9, Recombinant, Mouse (GDF9) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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