| 产品详情 |
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| Product Name | S49076 |
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| Description | Purity 98%. S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3. S49076 potently blocked cellular phosphorylation of MET, AXL, and FGFRs and inhibited downstream signaling in vitro and in vivo. In cell models, S49076 inhibited the proliferation of MET- and FGFR2-dependent gastric Y cells, blocked MET-driven migration of lung carcinoma cells, and inhibited colony formation of hepatocarcinoma cells expressing FGFR1/2 and AXL. In tumor xenograft models, a good pharmacokinetic/pharmac |
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| Size | 2 mg, 1ml/10mM (In DMSO), 5 mg, 10 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | CAS: 1265965-22-7 |
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| Catalog # | MBS578326 |
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| Price | |
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| Order / More Info | S49076 from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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