| 产品详情 |
| Edit |   |
|---|
| Product Name | Papillomavirus Type 52 Protein E7, Recombinant, Human, aa1-99, His-SUMO-Tag (E7) |
|---|
| Description | Purity ~90% (SDS-PAGE). E7 protein has both transforming and trans-activating activities. Disrupts the function of host retinoblastoma protein RB1/pRb, which is a key regulator of the cell cycle. Induces the disassembly of the E2F1 transcription factors from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. Interferes with histone deacetylation mediated by HDAC1 and HDAC2, leading to activation of transcription. Source: Recombinant protein corresponding to aa1-99 from human Papillomavirus Type 52 Protein E7, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~27kD AA |
|---|
| Size | 10ug, 50ug, 100ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | SwissProt: P36831 |
|---|
| Catalog # | 374613 |
|---|
| Price | |
|---|
| Order / More Info | Papillomavirus Type 52 Protein E7, Recombinant, Human, aa1-99, His-SUMO-Tag (E7) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|