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| Product Name | DPH2, 1-489aa, Human, His-tag, Baculovirus |
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| Description | MW: 53.1kDa (497aa) 50-70kDa (SDS-PAGE under reducing conditions). Purity >85% by SDS-PAGE. DPH2, also known as diphthamide biosynthesis protein 2, is a homodimer and each of its monomers can bind a [4Fe-4S] cluster. It is the target of ADP ribosylating diphtheria toxin (DT) and Pseudomonas exotoxin A (PE). It was identified by its ability to complement a diphthamide mutant strain, and thus functions in diphthamide biosynthesis. Its loss pre-activates NF-kB and death receptor pathways and render |
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| Size | 0.01 mg, 0.05 mg |
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| Concentration | 0.5 mg/ml (determined by Absorbance at 280nm) |
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| Applications | SDS-PAGE |
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| Other Names | [Diphthamide biosynthesis protein 2; DPH2; DPH2L2] |
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| Gene, Accession, CAS # | DPH2, Gene ID: 1802, Accession: NP_001375 |
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| Catalog # | MBS206632 |
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| Order / More Info | DPH2, 1-489aa, Human, His-tag, Baculovirus from MYBIOSOURCE INC. |
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| Product Specific References | Zhang Y., et al. (2010) Nature. 465:891-896.; Mattheakis LC., et al. (1993) Gene. 132:149-154. |
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