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| Product Name | Recombinant Human Corticotropin-releasing factor receptor 1 |
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| Description | 24-121aa; Partial. MW: 38.3kD. Purity >90% as determined by SDS-PAGE. G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.05 mg (Yeast), 0.2 mg (Yeast) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Corticotropin-releasing hormone receptor 1; CRH-R-1; CRH-R1] |
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| Gene, Accession, CAS # | CRHR1, Gene ID: 1394, Accession: NP_001138618.1 |
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| Catalog # | MBS967538 |
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| Order / More Info | Recombinant Human Corticotropin-releasing factor receptor 1 from MYBIOSOURCE INC. |
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| Product Specific References | Expression cloning of a human corticotropin-releasing-factor receptor.Chen R., Lewis K.A., Perrin M.H., Vale W.W.Proc. Natl. Acad. Sci. U.S.A. 90:8967-8971(1993) Primary structure and functional expression of mouse pituitary and human brain corticotrophin releasing factor receptors.Vita N., Laurent P., Lefort S., Chalon P., Lelias J.-M., Kaghad M., le Fur G., Caput D., Ferrara P.FEBS Lett. 335:1-5(1993) The genomic organization of the human corticotropin-releasing factor type-1 receptor.Sakai K. |
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