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| Product Name | Nucleoprotein, Recombinant, Rabies Virus, aa1-450, His-Tag (N) |
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| Description | Purity ~90% (SDS-PAGE). Encapsidates the genome in a ratio of one protein N per nine ribonucleotides, protecting it from nucleases. If expressed without protein P it binds non-specifically RNA and therefore can bind it's own mRNA. Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation. The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace. The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication. Protein N binds protein P in the NC through a different interaction, and can be phosphorylated. Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N. During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases. Source: Recombinant protein corresponding to aa1-450 from rabies virus N, fused to His-Tag at N-terminal, expre |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Nucleocapsid protein, Protein N |
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| Gene, Accession, CAS # | SwissProt: P15197 |
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| Catalog # | 374509 |
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| Order / More Info | Nucleoprotein, Recombinant, Rabies Virus, aa1-450, His-Tag (N) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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