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Product Name | Recombinant Human IGF-BP3 Protein |
Description | IGF-BP3 is a 30 kDa cysteine-rich secreted protein. It is the major IGF binding protein present in the plasma of human and animals and it is also found in α-granules of platelets. In addition to its ability to modulate the activity of IGF-I and IGF-II, IGF-BP3 exerts inhibitory effects on follicle stimulating hormone (FSH) activity. Decreased plasma levels of IGF-BP3 often results in dwarfism, whereas elevated levels of IGF-BP3 may lead to acromegaly. The expression of IGF-BP3 in fibroblasts is stimulated by mitogenic growth factors such as Bombesin, Vasopressin, PDGF, and EGF. Recombinant human IGF-BP3 is a 28.8 kDa protein consisting of 264 amino acid residues. |
Size | Various Sizes |
Concentration | n/a |
Applications | Cell Culture |
Other Names | Insulin-like growth factor-binding protein 3;IBP-3;IGF-binding protein 3;IGFBP-3;IGFBP3;IBP3; Insulin-like Growth Factor-Binding Protein 3, Growth-hormone-dependant binding protein |
Gene, Accession, CAS # | IGFBP3, UniProt: P17936 |
Catalog # | PROTP17936-2 |
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Order / More Info | Recombinant Human IGF-BP3 Protein from BOSTER BIO |
Product Specific References | n/a |
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