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| Product Name | CD28 IgG2a Fc, Fusion Protein (Biotin) |
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| Description | Purified by Protein A affinity chromatography. Human CD28 is an important costimulatory molecule found on all CD4+ T cells and on about half of the CD8+ T cells. T cell activities attributed to CD28 include, prevention of anergy, induction of cytokine gene transcription, stabilization of cytokine mRNAs and activation of CD8+ cytotoxic T lymphocytes. The ligands for CD28, identified as CD80 (B7-1) and CD86 (B7-2), are immunoglobulin superfamily monomeric transmembrane glycoproteins of 60kD and 80kD, respectively. Molecular Structure: A soluble fusion protein consisting of the extracellular (134 aa) domain of human CD28 fused to murine IgG2a Fc (232 aa), with a predicted monomeric molecular weight of 41.8kD. Transfectant Cell Line: CHO Human CD28-muIg/Biotin Fusion Protein Functional Application: CD28-muIg fusion protein blocks binding of anti-human CD28 to human tumor cells. Applications: Suitable for use in ELISA and Antibody Blocking. Recommended Dilution ELISA: 0.5ng/ml detects the f |
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| Size | 25ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | C2380-03F |
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| Order / More Info | CD28 IgG2a Fc, Fusion Protein (Biotin) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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