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| Product Name | CD80 IgG2a Fc & Hinge Region, Fusion Protein (B7-1 Costimulator Protein) |
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| Description | Purified from tissue culture supernatant of CHO transfectants. CD80, also known as BB1/B7-1, is a 60kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed on activated B cells, T cells, monocytes and dendritic cells. It is a ligand of the two T cell costimulatory molecules, CD28 and CD152 (CTLA-4). The interaction of CD80 (or CD86) with CD28 provides a costimulatory signal for T cells activated through the CD3/TCR complex. Molecular Structure: A soluble dimeric fusion protein consisting of the extracellular (173aa) domain of human CD80 fused to murine IgG2a Fc + hinge (232 aa), with a predicted monomeric molecular weight of 51.3kD. Functional Application: CD80-muIg fusion protein blocks binding of anti-human CD80 to human tumor cells. Applications: Suitable for use in ELISA, Flow cytometry and Antibody Blocking. Recommended Dilution Optimal dilutions to be determined by the researcher. |
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| Size | 25ug |
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| Concentration | n/a |
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| Applications | ELISA FC |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | C2432-01H |
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| Order / More Info | CD80 IgG2a Fc & Hinge Region, Fusion Protein (B7-1 Costimulator Protein) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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