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| Product Name | Recombinant Human Tyrosine-protein kinase Lck |
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| Description | 1-539aa; Full Length of Isoform 3. MW: 77.2kD. Purity >90% as determined by SDS-PAGE. Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T-cells in the thymus and in the function of mature T-cells. Plays a key role in T-cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the cytoplasmic portions of the CD4 and CD8 surface receptors. Association of the TCR with a peptide antigen-bound MHC comp |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Leukocyte C-terminal Src kinase; LSK; Lymphocyte cell-specific protein-tyrosine kinase; Protein YT16; Proto-oncogene Lck; T cell-specific protein-tyrosine kinase; p56-LCK] |
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| Gene, Accession, CAS # | LCK, Gene ID: 3932, Accession: NP_001036236.1 |
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| Catalog # | MBS948394 |
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| Order / More Info | Recombinant Human Tyrosine-protein kinase Lck from MYBIOSOURCE INC. |
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| Product Specific References | A human T cell-specific cDNA clone (YT16) encodes a protein with extensive homology to a family of protein-tyrosine kinases.Koga Y., Caccia N., Toyonaga B., Spolski R., Yanagi Y., Yoshikai Y., Mak T.W.Eur. J. Immunol. 16:1643-1646(1986) Structure and expression of lck transcripts in human lymphoid cells.Perlmutter R.M., Marth J.D., Lewis D.B., Peet R., Ziegler S.F., Wilson C.B.J. Cell. Biochem. 38:117-126(1988) Structure of the human lck genedifferences in genomic organisation within src-related |
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