| 产品详情 |
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| Antigenic Specificity | Thymidine Phosphorylase (TYMP) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse, rat, human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (IHC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Thymidine phosphorylase (TP) is a platelet-derived endothelial cell growth factor (PD-ECGF) that catalyzes the formation of thymine and 2-deoxy-D-ribose-1-phosphate from thymidine and orthophosphate . This intracellular enzyme is capable of both promoting angiogenesis and inhibiting apoptosis. Thymidine phosphorylase catalytic activity is required for its angiogenic function . Increased expression of TP/PD-ECGF is seen in a wide variety of different solid tumors and inflammatory diseases and is often associated with poor prognosis . Alternatively, TP can activate fluorouracil derivative (DFUR) prodrugs and increase the antitumor activity of the related treatment . The use of thymidine phosphorylase as a cancer therapeutic target has been studied extensively, with emphasis on either inhibiting TP enzymatic activity or increasing enzyme induction with concomitant DFUR treatment . Synonyms: TYMP,ECGF1,MNGIE,PDECGF,TP,hPD-ECGF , |
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| Immunogen | Recombinant protein of human TYMP |
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| Other Names | typh|CD363|CHEDG1|D1S3362|ECGF1|EDG-1|EDG1|S1P1|ECGF|MEDPS1|MNGIE|MTDPS1|PDECGF|TP|hPD-ECGF|Ecgf1|2900072D10Rik|PD-ECGF|Pdgfec |
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| Gene, Accession # | Gene ID: 1890,72962,315219 |
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| Catalog # | ABIN1684079 |
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| Price | |
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| Order / More Info | Thymidine Phosphorylase (TYMP) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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