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| Product Name | Securin, Recombinant, Human |
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| Description | Purity ~80% by SDS-PAGE Purified by immunoaffinity chromatography. PTTG1, also known as Securin, is primarily involved in the regulation of sister chromatid separation during cell division. It has two identified roles; the first one is to help the transport of separase(cysteine protease) to the nucleus and the second role is to inhibit the catalytic activity of separase. It is ubiquitinated by the Anaphase Promoting Complex (APC), and then degraded by the Proteasome, releasing separase. Recombinant PTTG1 protein , expressed in E. coli and purified by using conventional chromatography techniques. Source: Recombinant human PTTG1, aa1-202, His-tagged, expressed in E. coli AA Sequence: MGSSHHHHHH SSGLVPRGSH MATLIYVDKE NGEPGTRVVA KDGLKLGSGP SIKALDGRSQ VSTPRFGKTF DAPPALPKAT RKALGTVNRA TEKSVKTKGP LKQKQPSFSA KKMTEKTVKA KSSVPASDDA YPEIEKFFPF NPLDFESFDL PEEHQIAHLP LSGVPLMILD EERELEKLFQ LGPPSPVKMP SPPWESNLLQ SPSSILSTLD VELPPVCCDI DI Applications: Suitable for use in ELISA and Western Blot. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Securin, Recombinant, Human (Cut2, ESP1-associated Protein 1, EAP1, hPTTG, MGC126883, MGC138276, Pds1, Pituitary Tumor Transforming 1, PTTG, PTTG1, TUTR1) |
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| Gene, Accession, CAS # | Accession: NP_004210 |
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| Catalog # | S0379-80B |
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| Order / More Info | Securin, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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