| 产品详情 |
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| Product Name | Cornulin, Recombinant, Human |
| Description | Purity ~ 85% (SDS-PAGE). Purified by using conventional chromatography techniques. CRNN is a member of the fused gene family of proteins, which contain N-terminus EF-hand domains and multiple tandem peptide repeats. It contains two EF-hand Ca2+ binding domains in its N-terminus and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. This protein, also known as Survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines, attenuates deoxycholic acid (DCA)-induced apoptotic cell death and release of calcium. When overexpressed in oral squamous carcinom cell lines, regulates negatively cell proliferation by the induction of G1 arrest. Recombinant CRNN protein was expressed in E. coli. Source: Recombinant corresponding to aa1-495 of human CRNN 6x His tagged expressed in E. coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MPQLLQNING IIEAFRRYAR TEGNCTALTR GELKRLLEQE FADVIVKPHD PATVDEVLRL LDEDHTGTVE FKEFLVLVFK VAQACFKTLS ESAEGACGSQ ESGSL |
| Size | 100ug |
| Concentration | n/a |
| Applications | WB |
| Other Names | Cornulin, Recombinant, Human (CRNN, 53kD Putative Calcium-binding Protein, 53kD Squamous Epithelial-induced Stress Protein, 58kD Heat Shock Protein, C1orf10, DRC1, PDRC1, Squamous Epithelial Heat Shock Protein 53, SEP53, Tumor-related Protein) |
| Gene, Accession, CAS # | Accession: AAH30807 |
| Catalog # | C7901-10H |
| Price | |
| Order / More Info | Cornulin, Recombinant, Human from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
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