| 产品详情 |
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| Product Name | PDE3B, Active |
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| Description | 654-end. MW: ~85 kDa. Description: Recombinant human PDE3B (654-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: PDE3B is a member of the phosphodiesterase family of proteins that play a critical role in regulating intracellular levels of cAMP and cGMP. PDE3B has high affinity for cAMP and is inhibited by cGMP as well as specific inhibitors such as cilostamide and milrinone. PDE3B is phosphorylated and activated in response to insulin a |
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| Size | 0.005 mg, 0.01 mg |
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| Concentration | n/a |
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| Applications | PDE Assay |
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| Other Names | [Homo sapiens phosphodiesterase 3B (PDE3B), mRNA; cGMP-inhibited 3',5'-cyclic phosphodiesterase B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B; phosphodiesterase 3B; CGIPDE1; CGIP1; Cyclic GMP-inhibited phosphodiesterase B; CGI-PDE B] |
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| Gene, Accession, CAS # | PDE3B, Gene ID: 5140, Accession: NM_000922.3 |
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| Catalog # | MBS515629 |
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| Order / More Info | PDE3B, Active from MYBIOSOURCE INC. |
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| Product Specific References | 1. Zhao A Z, et al: A phosphatidylinositol 3-kinase-phosphodiesterase 3B-cyclic AMP pathway in hypothalamic action of leptin on feeding. Nature Neurosci. 5: 727-728, 2002. 2. Choi Y H, et al: Alterations in regulation of energy homeostasis in cyclic nucleotide phosphodiesterase 3B-null mice. J. Clin. Invest. 116: 3240-3251, 2006. |
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