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| Product Name | PDE4B, Active |
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| Description | 305-end. MW: ~78 kDa. Description: Recombinant human PDE4B (305-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: PDE4B is a member of the phosphodiesterase family of proteins that play a critical role in regulating intracellular levels of cAMP and has homology to the 'dunce' gene of Drosophila. The 'dunce' gene is one of several genes critical for normal learning and memory in the fly. Altered activity of PDE4B has been associated with |
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| Size | 0.005 mg, 0.01 mg |
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| Concentration | n/a |
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| Applications | PDE Assay |
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| Other Names | [Homo sapiens phosphodiesterase 4B (PDE4B), transcript variant a, mRNA; cAMP-specific 3',5'-cyclic phosphodiesterase 4B; cAMP-specific 3',5'-cyclic phosphodiesterase 4B; phosphodiesterase 4B; DPDE4; PDE32] |
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| Gene, Accession, CAS # | PDE4B, Gene ID: 5142, Accession: NM_002600.3 |
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| Catalog # | MBS515631 |
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| Order / More Info | PDE4B, Active from MYBIOSOURCE INC. |
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| Product Specific References | 1. Millar J K, et al: DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling. Science 310: 1187-1191, 2005. 2. Numata S, et al: Gene expression and association analyses of the phosphodiesterase 4B (PDE4B) gene in major depressive disorder in the Japanese population. Am J Med Genet B Neuropsychiatr Genet. 2009 Jun 5;150B (4):527-34. |
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