| 产品详情 |
| Edit |   |
|---|
| Product Name | PDE7B, Active |
|---|
| Description | Full Length. MW: ~73 kDa. Description: Full-length recombinant human PDE7B was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: PDE7B is a cAMP-specific phosphodiesterase and a member of the cyclic nucleotide phosphodiesterase family that catalyzes the hydrolysis of cAMP to the corresponding 5'-monophosphate and provides a mechanism to downregulate cAMP signaling (1). PDE7B is over-expressed in chronic lymphocytic leukemia and inhibition of PDE7 |
|---|
| Size | 0.005 mg, 0.01 mg |
|---|
| Concentration | n/a |
|---|
| Applications | PDE Assay |
|---|
| Other Names | [Homo sapiens phosphodiesterase 7B (PDE7B), mRNA; cAMP-specific 3',5'-cyclic phosphodiesterase 7B; cAMP-specific 3',5'-cyclic phosphodiesterase 7B; phosphodiesterase 7B] |
|---|
| Gene, Accession, CAS # | PDE7B, Gene ID: 27115, Accession: NM_018945.3 |
|---|
| Catalog # | MBS515638 |
|---|
| Price | |
|---|
| Order / More Info | PDE7B, Active from MYBIOSOURCE INC. |
|---|
| Product Specific References | 1. Hetman, J. M. et.al: Cloning and characterization of PDE7B, a cAMP-specific phosphodiesterase. Proc. Nat. Acad. Sci. 97: 472-476, 2000. 2. Ikeda, M. et al: Identification of novel candidate genes for treatment response to risperidone and susceptibility for schizophrenia: integrated analysis among pharmacogenomics, mouse expression, and genetic case-control association approaches. Biol Psychiatry. 2010 Feb 1;67 (3):263-9. |
|---|
| 产品资料 |
|
|