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| Product Name | Recombinant Human Interferon-induced helicase C domain-containing protein 1 (IFIH1), partial |
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| Description | 700-1025aa; Partial. MW: 53.5kDa. Purity ≥90%. Innate immune receptor which acts as a Cytoplasmic domain sensor of viral nucleic acids and plays a major role in sensing viral infection and in the activation of a cascade of antiviral responses including the induction of type I interferons and proinflammatory cytokines. Its ligands include mRNA lacking 2'-O-methylation at their 5' cap and long-dsRNA (>1 kb in length). Upon ligand binding it associates with mitochondria antiviral signaling prote |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Clinically amyopathic dermatomyositis autoantigen 140 kDa; CADM-140 autoantigen; Helicase with 2 CARD domains; Helicard; Interferon-induced with helicase C domain protein 1; Melanoma differentiation-associated protein 5; MDA-5; Murabutide down-regulated protein; RIG-I-like receptor 2; RLR-2; RNA helicase-DEAD box protein 116] |
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| Gene, Accession, CAS # | IFIH1; IFIH1; AGS7; Hlcd; MDA5; MDA-5; RLR-2; IDDM19; SGMRT1; MDA5; RH116; CADM-140 autoantigen; Helicard; MDA-5; RLR-2, Gene ID: 64135, Accession: NP_071451.2 |
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| Catalog # | MBS7100621 |
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| Price | |
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| Order / More Info | Recombinant Human Interferon-induced helicase C domain-containing protein 1 (IFIH1), partial from MYBIOSOURCE INC. |
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| Product Specific References | mda-5: an interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties.Kang D.-C., Gopalkrishnan R.V., Wu Q., Jankowsky E., Pyle A.M., Fisher P.B.Proc. Natl. Acad. Sci. U.S.A. 99:637-642(2002) |
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