| 产品详情 |
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| Product Name | TCS 401 |
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| Description | Purity >95%. TCS 401 is a selective inhibitor of protein-tyrosine phosphatase 1B (PTP1B; Ki = 0.29 µM). It inhibits the protein phosphatases CD45 D1D2, PTPBeta, PTPe D1, SHP-1, PTPAlpha D1, and LAR D1D2 at much higher concentrations (Ki s = 59, 560, 1,100, >2,000, >2,000, and >2,000 µM, respectively). Several PTPs have been proposed to act as negative regulators of insulin signaling, thus this enzyme is a potential drug target in diabetes. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-[(carboxycarbonyl)amino]-4,5,6,7-tetrahydro-thieno[2,3-c]pyridine-3-carboxylic acid, monohydrochloride |
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| Gene, Accession, CAS # | CAS: 243966-09-8 |
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| Catalog # | LS-H10125 |
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| Order / More Info | TCS 401 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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