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| Product Name | TCS 5861528 |
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| Description | Purity >98%. The transient receptor potential ankyrin 1 (TRPA1) ion channel integrates the nociception and transmission of diverse, potentially damaging and noxious stimuli, including cold, electrophilic compounds, divalent cations, and mechanical stimulation. TCS 5861528 is a selective TRPA1 blocker that antagonizes TRPA1-mediated calcium influx induced by allyl isothiocyanate and 4-hydroxy nonenal with IC50 values of 14.3 and 18.7 µM, respectively. At 30 mg/kg twice daily in rats, TCS 5861528 has been used to attenuate pain-related behavior in models of diabetic hypersensitivity and postoperative pain. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1,2,3,6-tetrahydro-1,3-dimethyl-N-[4-(1-methylpropyl)phenyl]-2,6-dioxo-7H-purine-7-acetamide |
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| Gene, Accession, CAS # | CAS: 332117-28-9 |
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| Catalog # | LS-H10129 |
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| Order / More Info | TCS 5861528 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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