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| Product Name | Mouse Interleukin-25 Recombinant |
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| Description | MW: 17,982 Da. Purity >95%, as determined by SDS-PAGE and HPLC. IL-25 (also known as IL- 17E), a member of the IL-17 family, has been implicated in Th2 cell-mediated immunity. Recently, IL-25 has been identified as one of the initiators of the Th2 response (10, 11) and has also been shown to be expressed by mast cells. The transgenic overexpression of IL-25 by lung epithelial cells results in mucus hyperproduction and airway infiltration of macrophages and eosinophils; conversely, IL-25 blockade |
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| Size | 0.002 mg, 0.01 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [il17e; SF20; il25; interleukin-25; il-25] |
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| Gene, Accession, CAS # | IL-25, Gene ID: 28106, Accession: NP_543027.1 |
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| Catalog # | MBS553229 |
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| Order / More Info | Mouse Interleukin-25 Recombinant from MYBIOSOURCE INC. |
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| Product Specific References | • t-helper cell type 2 (th2) memory t cell-potentiating cytokine IL-25 has the potential to promote angiogenesis in asthma .PNAS, Jan 2011; 10.1073/pnas.1014241108. • critical role of IL-25 in nematode infection-induced alterations in intestinal function .J. Immunol., Dec 2010; 185: 6921 - 6929. • nk cell deficiency predisposes to viral-induced th2-type allergic inflammation via epithelial-derived IL-25 .J. Immunol., Oct 2010; 185: 4681 - 4690. • overexpression of smad2 drive |
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