产品详情 |
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Antigenic Specificity | Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) (aa 22-125) |
Clone | Plc12AT |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 20 µg |
Concentration | n/a |
Applications | ELISA,Western Blotting (WB),Immunofluorescence (Cultured Cells) (IF (cc)),Flow Cytometry (FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | LAIR1 is a glycoprotein (32 kDa) expressed on the surface of the majority of human peripheral blood mononuclear leukocytes including T cells, B cells, NK cells, macrophages and dendritic cells. LAIR-1 functions as an inhibitory receptor in NK cells, T cells and B cells. Inhibitory receptors control the immune response to prevent lysis of cells recognized as self. Lair-1 consists of a leader sequence, extracellular domain, transmembrane domain, cytoplasmic region. LAIR1 is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. LAIR1 maps to a region of 19q13.4 labeled the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamilySynonyms: Leukocyte-associated immunoglobulin-like receptor 1, LAIR-1, hLAIR1, CD305 antigen, LAIR1, CD305 |
Immunogen | Anti-human LAIR1 mAb, is derived from hybridization of mouse SP2/0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human LAIR-1 AA 22-125 |
Other Names | 5133400O11Rik|BB115266|D7Bwg0421e|Lair-1|mLair-1|CD305|LAIR-1 |
Gene, Accession # | Gene ID: 3903 |
Catalog # | ABIN808488 |
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Order / More Info | Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) (aa 22-125) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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