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Antigenic Specificity | CD52 Molecule (CD52) |
Clone | BTG-2G |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a |
Format | fluorescein (FITC) conjugate |
Size | 100 µL |
Concentration | n/a |
Applications | Flow Cytometry (FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CAMPATH-1, also known as CD52, is a heavily glycosylated, GP I-anchored protein expressed at high levels on almost all thymocytes, lymphocytes, monocytes, and macrophages. CAMPATH-1 is an exceptionally good target for complement-mediated cell lysis and antibody-mediated cellular cytotoxicity. Humanized CAMPATH-1 antibodies have been used therapeutically to effectively deplete lymphocytes in allogeneic bone marrow transplants, hematologic malignancies, and autoimmune diseases. Clinical trials suggest CAMPATH-1 antibodies are especially promising in the treatment of leukemia, non-Hodgkin lymphomas, and rh eumatoid arth ritis. The apparent size of CAMPATH-1 by SDS-PAGE is 25-29 kDa, however, the actual molecule is much smaller, ~ 8-9 kDa as confirmed by total structure analysis and mass spectrometry.Synonyms: CDw52, Cambridge pathology 1 antigen, Epididymal secretory protein E5, HE5 |
Immunogen | Mouse IL-2Ralpha-transgenic mouse splenocyte |
Other Names | CD52|AI463198|B7|B7-Ag|CAMPATH-1|CLS1|MB7|CDW52|CE5 |
Gene, Accession # | Gene ID: 23833 |
Catalog # | ABIN2853609 |
Price | |
Order / More Info | CD52 Molecule (CD52) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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