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| Product Name | Sorbitol Dehydrogenase Activity Assay Kit (Colorimetric) |
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| Description | Sorbitol Dehydrogenase (SDH), also referred to as L-iditol dehydrogenase (EC 1.1.1.14) participates in the polyol pathway. Also known as the sorbitol-aldose pathway, this pathway is divided into two steps: first, glucose is reduced to sorbitol via the catalytic action of aldose reductase (AR), while the second step is catalyzed by sorbitol dehydrogenase, which utilizes sorbitol as substrate and subsequently produces fructose. Sorbitol is not a cell membrane permeable molecule; whereas fructose can be further metabolized inside the cells. Recent studies found that deficiency of Sorbitol Dehydrogenase causes the intracellular accumulation of sorbitol which leads complications in diabetes. The enzyme is predominately expressed in the liver cel |
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| Size | 100 assays |
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| Concentration | n/a |
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| Applications | • Measurement of Sorbitol Dehydrogenase Activity in various tissues/cells. • Analysis of polyol-pathway.• Studies of chemically-induced hepatotoxicity and acute liver injury.• Freshly obtained serum from animals with suspected liver damage |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | K935-100 |
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| Order / More Info | Sorbitol Dehydrogenase Activity Assay Kit (Colorimetric) from BIOVISION, INC. |
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| Product Specific References | n/a |
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