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| Product Name | N-myc Downstream Regulated Gene 1, Recombinant, Human (NDRG1) |
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| Description | Purity ~95% by SDS-PAGE Purified by immunoaffinity chromatography. N-myc downstream regulated gene (NDRG)-1 is one of 4 members of the NDRG α/β-hydrolase family. This protein is classified in databases as a tumor suppressor and heavy metal-response protein. Its functions include cell-cycle regulation, cellular differentiation, apoptosis, hypoxia response and metal-ion sensing. Mutation in the NDRG1 gene has been reported to be causative for hereditary motor and sensory neuropathy-Lom (HMSNL), a severe autosomal recessive form of Charcot-Marie-Tooth (CMT) disease. Recombinant human NDRG1, fused to His-tag at C-terminus, , expressed in E. coli and purified by using conventional chromatography. Source: Recombinant human NDRG1, aa1-394 His-tagged, expressed in E. coli AA Sequence: MSREMQDVDL AEVKPLVEKG ETITGLLQEF DVQEQDIETL HGSVHVTLCG TPKGNRPVIL TYHDIGMNHK TCYNPLFNYE DMQEITQHFA VCHVDAPGQQ DGAASFPAGY MYPSMDQLAE MLPGVLQQFG LKSIIGMGTG AGAYILTRFA LNNPEMVEGL VLINVNPCAE GWMDWAASKI SGW |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_006087 |
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| Catalog # | N2915-51 |
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| Order / More Info | N-myc Downstream Regulated Gene 1, Recombinant, Human (NDRG1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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