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| Antigenic Specificity | Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (aa 42-335) |
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| Clone | DR-6-04-EC |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | phycoerythrin (PE) conjugate |
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| Size | 0.1 mg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FACS) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD358 / DR6 (Death Receptor-6) is a type I transmembrane protein of the TNF receptor superfamily, expressed in most human tissues and able of inducing apoptosis through its cytoplasmic death domain. Unlike TNFR1 and Fas, DR6 induces apoptosis independently of FADD adaptor. In immune system, DR6 serves as an important regulator for CD4+ T cell proliferation and Th differentiation, and provides also a regulatory mechanism for B cell activation and humoral immune responses. |
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| Immunogen | A fusion protein representing amino acids 42-335 (extracellular part) of human DR6 linked to the Fc portion of human IgG1 was used as an immunogen. |
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| Other Names | TNFRSF21|tnfrsf21|MGC146356|BM-018|CD358|DR6|AA959878|R74815|TR7|dr6|im:6795346|wu:fa55e01|wu:fb02e11|wu:fc29a09|wu:fi27h08 |
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| Gene, Accession # | Gene ID: 27242 |
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| Catalog # | ABIN192317 |
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| Price | |
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| Order / More Info | Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (aa 42-335) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 11753679, 9714541, 12515813, 12604411 |
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