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| Product Name | RD162 |
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| Description | Purity >98%. RD162 is a second-generation androgen receptor (AR) antagonist. It inhibits binding of 18 F-FDHT to AR in human prostate cancer cells with an IC50 value of 30.9 nM. RD162 completely suppresses VCaP cell proliferation at 1 µM and induces apoptosis of VCaP cells at 10 µM. RD162 is bioavailable and reduces LNCaP/AR tumor growth in castrated male mice at a daily oral dose of 10 mg/kg. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-[7-[4-cyano-3-(trifluoromethyl)phenyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-5-yl]-2-fluoro-N-methyl-benzamide |
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| Gene, Accession, CAS # | CAS: 915087-27-3 |
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| Catalog # | LS-H9667 |
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| Price | |
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| Order / More Info | RD162 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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