| 产品详情 |
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| Product Name | Sp-8-bromo-Cyclic AMPS (sodium salt) |
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| Description | Purity >98%. Sp-8-bromo-cyclic AMPS (Sp-8-bromo-cAMPS) is a cell-permeable, cAMP analog that combines an exocyclic sulfur substitution in the axial position of the cyclophosphate ring with a bromine substitution in the adenine base of cAMP. This configuration pools the structural features of two established cyclic-AMP-dependent protein kinase (PKA) activators, 8-bromo-cAMP and Sp-cAMPS . Sp-8-bromo-cAMPS is a PKA agonist (EC50 = 1.5 µM) with improved lipophilicity and is not readily degraded by cyclic nucleotide phosphodiesterases. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (4aR,6R,7R,7aS)-6-(6-amino-8-bromo-9H-purin-9-yl)-7-hydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-2-olate 2-sulfide, monosodium salt, 8-Bromoadenosine 3',5'-cyclic Monophosphothioate SP-Isomer, Sp-8-bromo-cAMPS |
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| Gene, Accession, CAS # | CAS: 1573115-90-8 |
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| Catalog # | LS-H9983 |
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| Order / More Info | Sp-8-bromo-Cyclic AMPS (sodium salt) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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