| 产品详情 |
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| Product Name | CD437 |
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| Description | MW: 398.49. Purity >95%. Background: CD437 is the adamantyl arotinoid of the retinoid-related molecule family that acts as a selective agonist of retinoic acid receptor (RAR)gamma (Kds = 6.5 muM, 2.5 muM, and 77 nM for RARalpha, beta, and gamma, respectively). CD437 is cytotoxic to the acute myeloid leukemia cell line NB4 (EC?? = 0.17 muM), inducing DNA damage by producing DNA double strand breaks. CD437 also induces cell cycle arrest and apoptosis in various other cancer cells including melanom |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [6-?(4-?hydroxy-?3-?tricyclo[3.3.1.13,?7]dec-?1-?ylphenyl)-?2-?naphthalenecarboxylic acid; AHPN] |
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| Gene, Accession, CAS # | CAS: 125316-60-1 |
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| Catalog # | MBS842952 |
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| Order / More Info | CD437 from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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