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Product Name | SM-164 |
Description | SM-164 is a potent cell-permeable and bivalent Smac mimetic which binds to a XIAP protein with a Ki value of 0.56 nM, and binds to cIAP-1 and cIAP-2 proteins with Ki values of 0.31 and 1.1 nM, respectively. It displays antitumor properties through inducing degradation of cellular inhibitor of apoptosis protein (cIAP)-1/2, antagonizing X-linked inhibitor of apoptosis protein (XIAP) and inducing TNFα-dependent apoptosis in tumor cells. MW: 1121.42. Purity ≥98% by HPLC |
Size | 250 µg |
Concentration | n/a |
Applications | n/a |
Other Names | (3S,3'S,6S,6'S,10aS,10a'S)-N,N'-((1S,1'S)-((1,4-phenylenebis(butane-4,1-diyl))bis(1H-1,2,3-triazole-1,4-diyl))bis(phenylmethylene))bis(6-((S)-2-(methylamino)propanamido)-5-oxodecahydropyrrolo[1,2-a]azocine-3-carboxamide) |
Gene, Accession, CAS # | CAS: 957135-43-2 |
Catalog # | B1816-250 |
Price | |
Order / More Info | SM-164 from BIOVISION, INC. |
Product Specific References | n/a |
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