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Antigenic Specificity | Nuclear Receptor Binding SET Domain Protein 1 (NSD1) |
Clone | 2658C1a |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | Protein G purified |
Size | 50 µg |
Concentration | n/a |
Applications | Dot Blot (DB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98 kDa on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene. Synonyms: Monoclonal NSD1 antibody, Anti-NSD1 antibody, Nuclear receptor binding SET domain protein 1 antibody, STO antibody, KMT3B antibody, SOTOS antibody, ARA267 antibody, FLJ22263 antibody, FLJ44628 antibody, DKFZp666C163 antibody. |
Immunogen | NSD1 antibody was raised in mouse using recombinant Human Nuclear Receptor Binding Set Domain Protein 1 (Nsd1) |
Other Names | NSD1|sto|kmt3b|sotos|ara267|ARA267|KMT3B|SOTOS|SOTOS1|STO|AI528500 |
Gene, Accession # | Gene ID: 64324 |
Catalog # | ABIN932477 |
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Order / More Info | Nuclear Receptor Binding SET Domain Protein 1 (NSD1) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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