| 产品详情 |
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| Antigenic Specificity | F4/80 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse, rat, human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 200 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (IHC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The epidermal growth factor (EGF)-TM7 family constitutes a group of class B G-protein coupled receptors, which includes CD97, EMR1 (EGF-like molecule containing mucin-like hormone receptor 1, designated F4/80 in mouse), EMR2, EMR3, FIRE, and ETL (1-3). These family members are characterized by an extended extracellular region with several N-terminal EGF domains, and are predominantly expressed on cells of the immune system (1-3). The EGF-TM7 protein family are encoded by a gene cluster on human chromosome 19p13. The F4/80 molecule is solely expressed on the surface of macrophages and serves as a marker for mature macrophage tissues, including Kupffer cells in liver, splenic red pulp macrophages, brain microglia, gut lamina propria, and Langerhans cells in the skin. F4/80/EMR1 undergoes extensive N-linked glycosylation as well as some O-linked glycosylation. The function of F4/80/EMR1 is unclear, but it is speculated to be involved in macrophage adhesion events, cell migration, or as a G-protein coupled signaling component of macrophages. Synonyms: Emr1, DD7A5-7, EGF-TM7, F4/80, Gpf480, Ly71, TM7LN3 |
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| Immunogen | A synthetic peptide of human F4-80 |
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| Other Names | DD7A5-7|EGF-TM7|F4/80|Gpf480|Ly71|TM7LN3 |
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| Gene, Accession # | Gene ID: 13733 |
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| Catalog # | ABIN1514062 |
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| Price | |
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| Order / More Info | F4/80 Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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