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| Product Name | CDK5P35 Recombinant protein |
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| Description | MW: ~60 kDa. Recombinant full-length human CDK5P35 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: CDK5P35 is a neuron-specific activator of cyclin-dependent kinase 5 (CDK5) that bind to cyclin to form active holoenzymes that play a pivotal role in the regulation of the eukaryotic cell cycle.The activation of CDK5 is required for proper development of the central nervous system. p35 is a regulatory subunit for CDK5 which is prote |
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| Size | 0.02 mg, 0.05 mg |
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| Concentration | n/a |
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| Applications | Kinase Assay, Western Blot (WB) |
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| Other Names | [p35; CDK5R1; CDK5R; NCK5A; p35nck5a] |
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| Gene, Accession, CAS # | CDK5P35, Gene ID: 8851, Accession: NP_003876.1 |
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| Catalog # | MBS515245 |
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| Order / More Info | CDK5P35 Recombinant protein from MYBIOSOURCE INC. |
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| Product Specific References | 1. Patrick, G. N.et.al: Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration. Nature 402: 615-622, 1999. 2. Chae, T. et.al: Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality. Neuron 18: 29-42, 1997. |
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