产品详情 |
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Antigenic Specificity | E Cadherin/CDH1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted: hamster) |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100ug (sample available) |
Concentration | 500ug/ml. |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit IgG polyclonal antibody for Cadherin-1(CDH1) detection. Tested with WB in Human. No cross reactivity with other proteins. CDH1(Cadherin 1), also known as ECAD or UVO, is a protein that in humans is encoded by the CDH1 gene. Cadherin-1 is a classical member of the cadherin superfamily. By Southern analysis of DNA from a panel of mouse-human somatic cell hybrids, Mansouri et al.(1987, 1988) assigned the UVO gene to 16q(16p11-qter). Frebourg et al.(2006) found that in human embryos CDH1 is highly expressed at 4 and 5 weeks in the frontonasal prominence and at 6 weeks in the lateral and medial nasal prominences, and is therefore expressed during critical stages of lip and palate development. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. |
Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human E Cadherin(662-677aa DYKINLKLMDNQNKDQ). |
Other Names | Cadherin-1;CAM 120/80;Epithelial cadherin;E-cadherin;Uvomorulin;CD324;E-Cad/CTF1;E-Cad/CTF2;E-Cad/CTF3;CDH1;CDHE, UVO; |
Gene, Accession # | CDH1, UniProt: P12830 |
Catalog # | PA2078 |
Price | |
Order / More Info | E Cadherin/CDH1 Antibody from BOSTER BIO |
Product Specific References | n/a |
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