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Product Name | Platelet Derived Growth Factor BB (PDGFBB) (Active) protein |
Description | PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs, PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet a-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-a and PDGFR-beta. PDGFR-a is high-affinity receptor for each of the three PDGF forms. Alternative Names: Osteosarcoma-derived Growth Factor protein, Platelet-Derived Growth Factor-BB protein, GDGF protein, Glioma-derived growth factor protein, ODGF protein |
Size | 10 µg |
Concentration | n/a |
Applications | n/a |
Other Names | PDGF-2|PDGF2|SIS|SSV|c-sis |
Gene, Accession, CAS # | n/a |
Catalog # | ABIN935706 |
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Order / More Info | Platelet Derived Growth Factor BB (PDGFBB) (Active) protein from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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