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| Product Name | Human CD32b Recombinant (FcgR2b) |
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| Description | MW: 34,044 Da. Purity >95%, as determined by SDS-PAGE and HPLC. Human CD32B (FcγRIIB), the low-affinity inhibitory Fcγ receptor (FcγR), is highly homologous in its extracellular domain to CD32A (FcγRIIA), an activating FcγR.CD32B is coexpressed with activating Fc receptors on monocytes, macrophages, basophils and mast cells. CD32B is also expressed by B lymphocytes, the sole FcγR expressed by these cells, where it functions by countering B- cell receptor (BCR) -indu |
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| Size | 0.02 mg, 0.1 mg, 0.5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Human CD32b Recombinant (Fcg RIIb) ; Human CD32b Recombinant (Fcgamma RIIb) ; cd32; cd-32; fcgr3a] |
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| Gene, Accession, CAS # | CD32, Gene ID: 2213, Accession: NP_001002273.1 |
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| Catalog # | MBS553152 |
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| Order / More Info | Human CD32b Recombinant (FcgR2b) from MYBIOSOURCE INC. |
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| Product Specific References | • CD32b expression reflects phenotypic and functional heterogeneity in multiple myeloma (mm) .Blood (ASH Annual Meeting Abstracts), Nov 2008; 112: 842. • CD32b is highly expressed on clonal plasma cells from patients with systemic light-chain amyloidosis and provides a target for monoclonal antibody-based therapy .Blood, Apr 2008; 111: 3403 - 3406. • an fc-optimized monoclonal antibody against CD32b, the human inhibitory fc- receptor iib, in the immunotherapy of b-cell malignanacy |
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