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| Product Name | Embelin |
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| Description | Purity >95%. X-Linked inhibitor of apoptosis (XIAP) is a protein which modulates several pathways, including several related to apoptosis. Embelin is a natural benzoquinone, isolated from plants of the genus Embelia, which directly binds and inhibits XIAP (IC50 = 4.1 µM). In this way, this cell-permeable inhibitor blocks growth while activating caspases and promoting apoptosis in cancer cells expressing high levels of XIAP. Presumably in an XIAP-dependent fashion, embelin (15-50 µM) also prevents NF-?B activation by inhibiting IKK. This compound also protects against XIAP- and caspase-dependent inflammation. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2,5-dihydroxy-3-undecyl-2,5-cyclohexadiene-1,4-dione, NSC 91874 |
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| Gene, Accession, CAS # | CAS: 550-24-3 |
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| Catalog # | LS-H7651 |
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| Order / More Info | Embelin from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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