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| Product Name | Recombinant Human Alpha-endosulfine protein |
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| Description | 1-121aa; Full Length. MW: 40.8kD. Purity >90% as determined by SDS-PAGE. Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. Also acts as a stimulator of insulin secretion by interacting with sulfonylurea receptor (ABC |
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| Size | 0.01 mg, 0.05 mg, 0.1 mg, 0.2 mg, 0.5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [ARPP-19e] |
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| Gene, Accession, CAS # | ENSA, Gene ID: 2029, Accession: NP_004427.1 |
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| Catalog # | MBS717164 |
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| Order / More Info | Recombinant Human Alpha-endosulfine protein from MYBIOSOURCE INC. |
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| Product Specific References | Human alpha-endosulfine, a possible regulator of sulfonylurea-sensitive K(ATP) channelmolecular cloning, expression and biological properties.Heron L., Virsolvy A., Peyrollier K., Gribble F.M., Le Cam A., Ashcroft F.M., Bataille D.Proc. Natl. Acad. Sci. U.S.A. 95:8387-8391(1998) Isolation, characterization, and chromosomal localization of the human ENSA gene that encodes alpha-endosulfine, a regulator of beta-cell K(ATP) channels.Heron L., Virsolvy A., Apiou F., Le Cam A., Bataille D.Diabetes 48 |
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