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| Product Name | PtdIns-(3,4,5)-P3-fluorescein (ammonium salt) |
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| Description | Purity >95%. The phosphatidylinositols (PtdIns) phosphates represent a small precentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(4,5)-P2 can be phosphorylated by phosphatidylinositol (PI)-3-kinase to make PtdIns-(3,4,5)-P3, which initiates an intricate signaling cascade that has been implicated in cancer. PtdIns-(3,4,5)-P3 fluorescein is a fluorescent probe for any protein with a high affinity binding interaction with inositol-(3,4,5)-triphosphate phospholipids, such as phosphatidylinositol 3-kinase, PTEN, or PH-domain-containing proteins. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-(1-octadecanoyl-fluorescein-2R-octanoylphosphatidyl)inositol-3,4,5-trisphosphate, heptatriethylammonium salt |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | LS-H9562 |
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| Order / More Info | PtdIns-(3,4,5)-P3-fluorescein (ammonium salt) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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