产品名称 PtdIns-(3,4,5)-P3 (1-stearoyl, 2-arachidonoyl) (sodium salt) from LIFESPAN BIOSCIENCES INC.
产品货号 LS-H9558
产品价格 现货询价,电话:010-67529703
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产品品牌 LIFESPAN BIOSCIENCES INC.
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Product NamePtdIns-(3,4,5)-P3 (1-stearoyl, 2-arachidonoyl) (sodium salt)
DescriptionPurity >98%. The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Centuarin Alpha and Akts are examples of PtdIns-(3,4,5)-P3 -binding proteins. Protein-binding to PtdIns-(3,4,5)-P3 is important for cytoskeletal rearrangements and membrane trafficking. PtdIns-(3,4,5)-P3 is resistant to cleavage by PI-specific PLC. Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates. For further reading on inositol phospholipids, see also references 5 and 6 .
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Other Names1-(1-octadecanoyl-2R-(5Z,8Z,11Z,14Z)-eicosatetraenoylphosphatidyl)inositol-3,4,5-trisphosphate, tetrasodium salt, Phosphatidylinositol-3,4,5-triphosphate C-18 (sodium salt)
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Catalog #LS-H9558
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Order / More InfoPtdIns-(3,4,5)-P3 (1-stearoyl, 2-arachidonoyl) (sodium salt) from LIFESPAN BIOSCIENCES INC.
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