| 产品详情 |
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| Product Name | PtdIns-(3,4,5)-P3 (1-stearoyl, 2-arachidonoyl) (sodium salt) |
| Description | Purity >98%. The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Centuarin Alpha and Akts are examples of PtdIns-(3,4,5)-P3 -binding proteins. Protein-binding to PtdIns-(3,4,5)-P3 is important for cytoskeletal rearrangements and membrane trafficking. PtdIns-(3,4,5)-P3 is resistant to cleavage by PI-specific PLC. Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates. For further reading on inositol phospholipids, see also references 5 and 6 . |
| Size | n/a |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 1-(1-octadecanoyl-2R-(5Z,8Z,11Z,14Z)-eicosatetraenoylphosphatidyl)inositol-3,4,5-trisphosphate, tetrasodium salt, Phosphatidylinositol-3,4,5-triphosphate C-18 (sodium salt) |
| Gene, Accession, CAS # | n/a |
| Catalog # | LS-H9558 |
| Price | |
| Order / More Info | PtdIns-(3,4,5)-P3 (1-stearoyl, 2-arachidonoyl) (sodium salt) from LIFESPAN BIOSCIENCES INC. |
| Product Specific References | n/a |
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