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| Product Name | PtdIns-(3,4,5)-P3 (1-stearoyl, 2-docosahexaenoyl) (sodium salt) |
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| Description | Purity >98%. Phosphatidyl inositol trisphosphate (PtdIns-(3,4,5)-P3 ) is a membrane phospholipid that may be cleaved by phospholipase C (PLC) to produce the second messengers inositol tetrakisphosphate (IP4 ) and diacylglycerol (DAG). IP4 triggers an increase in intracellular calcium. PtdIns-(3,4,5)-P3 (1-stearoyl, 2-docosahexaenoyl) is an uncommon phospholipid having the ?-3 fatty acid docosahexaenoate (DHA) in the sn -2 position. In addition to releasing an unusual DHA-containing DAG in response to PLC, this phospholipid can serve as a source of DHA in response to phospholipases A2 (PLA2 ). Importantly, the inositol head group of PtdIns-(3,4,5)-P3 can serve as an anchor for the binding of proteins bearing pleckstrin homology (PH) domains. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-(1-octadecanoyl)-2R-(5Z,8Z,11Z,14Z)-eicosatetraenoylphosphatidyl)inositol-3,4,5-triphosphate, tetrasodium salt |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | LS-H9557 |
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| Order / More Info | PtdIns-(3,4,5)-P3 (1-stearoyl, 2-docosahexaenoyl) (sodium salt) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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